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Treating most cancers with excessive efficacy whereas eliminating negative effects has been the holy grail of most cancers analysis. The problem, nevertheless, arises from the similarity in molecular traits of most cancers cells and regular cells as a result of really particular most cancers biomarkers are extraordinarily scarce if not solely unavailable. Typically, biomarkers serving because the therapeutic targets are current on each wholesome cells and cancers, however at completely different ranges, inflicting not solely off-target negative effects but additionally on-target negative effects. This work has reported a brand new idea of most cancers remedy, spatial confinement of cells to inhibit cell migration and invasion, which straight addresses the defining trait of most cancers on the mobile stage, unchecked division. Utilizing giant sized graphene oxide (LS-GO), cell surfaces could be patched. In contrast to typical chemotherapy, this spatial confinement doesn’t have an effect on the viability of non-dividing cells however considerably inhibits tumor cell migration and invasion in vitro and in vivo. This new idea has the potential to turn into a common therapeutic for a lot of most cancers sorts with decreased negative effects.
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